Curve up grades
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D1
D2
D3
D4
D5
ORI
.99
.01
.31
.13
.19
TRANS (sigmoid)
.95
.5
.72
.59
.64
Transform =
age = max(physical age*0.8, min((domain age(t-1) + 0.25*response + 0.25*(month_diff(t-1, t))), physical age*1.2)))